Entries by James M Roe

Poor sleep quality and Alzheimer’s biomarkers

Sleep is associated with many beneficial brain processes, including the strengthening of synaptic connections that correspond to memories and learnt material, and the clearance of potential neurotoxic proteins.   As we get older we have a general tendency to sleep less. Previous work in our lab has demonstrated an important link between self-reported poor sleep […]

Early life affects how we age – new PNAS paper

Older adults tend to vary considerably when it comes to performance on certain mental tasks; some older individuals perform very well while others perform quite poorly. However, we know that a person’s cognitive performance in later life tends to be somewhat similar across various mental tasks, such that high performance in one cognitive domain tends […]

Memory training: White matters

Throughout life the human brain is constantly changing and modifying itself to adapt to the changing demands of the environment. This so-called cognitive plasticity is an inherent characteristic of the brain that essentially reflects one’s ability to learn. Older individuals tend to vary substantially to the degree that they show improvement through cognitive intervention and […]